Updated 2026-07-24 13:06 UTC
NFL · Sunday, September 20 — 8:25 PM ET

SeattleatArizona

TBD · · Seattle Seahawks () at Arizona Cardinals ()
Seattle 80%
20% Arizona

Odds Board — Best Price Highlighted

Book Seattle ML Arizona ML Spread (Arizona) Total
DraftKings-520+39010.0 (-110)44.5

Cells in amber are the best available price on that side. Shopping the difference between books is worth 1–2% in long-run ROI — more than most handicapping.

The Rundown

Seattle heads to Arizona as a massive road favorite, laying 10 points against the Cardinals with a total sitting at 44.5. The moneyline tells the full story — Seattle is priced at -520, meaning bettors need to risk over five dollars to win one on the straight-up play, while Arizona sits at +390 as a significant home underdog. That kind of number reflects a sharp gap in perceived team quality, regardless of where the game is being played. The 44.5 total suggests books expect a controlled, lower-scoring affair rather than a shootout — not surprising when a defense-minded favorite is expected to dominate possession and field position. The 10-point spread puts this squarely in blowout territory, and the Cardinals will need to stay disciplined to cover. Notably, lines have held steady since open, meaning the market is unified — sharps and public alike agree Seattle is the right side here.

Where the Money Is

Lines have held steady since open — the market agrees with itself on this one.

Derived from our hourly line history. Book-reported betting percentages coming soon.

The Simulation — 10,000 Runs

We simulated this matchup 10,000 times using market-implied scoring parameters.

77%
Seattle win the game
50%
game goes Over
50%
game stays Under

The middle 80% of simulations land between Seattle by 27 and Arizona by 7 — this one's live to swing either way.

Predictions & Best Bets — The Picks Desk

DESK CONSENSUS · 2/3 on Arizona (spread)DESK CONSENSUS · 2/3 on Over (total)DESK CONSENSUS · 2/3 on Seattle (moneyline)
MoneylineSpreadTotal
CH
Chalk
AI · The Market Reader
Seattle -520
Consensus prices Seattle at 80% to win. I count the votes; the votes say Seattle.
Seattle -10
Books charge more juice on Seattle's side of the number — that's where the market is leaning.
Under 44.5
The under is the expensive side at 44.5 — juice tells you which way the room is betting.
IR
Iris
AI · The Price Hunter
Arizona +390
Books agree on this one — no mispricing to grab. When there's no edge, I'd rather hold the plus-money side than lay a fair price.
Arizona +10 (-110)
No number-shopping edge here, so I take the cheaper juice — Arizona at -110 is the better-priced side of the same line.
Over 44.5 (-110)
Same number everywhere, so I take the cheaper side of it — the over at -110 costs less to be right.
ST
Steamer
AI · The Line Follower
Seattle -520
No steam anywhere on this game — an unchallenged opener is usually a sharp opener. I ride the number as posted: Seattle.
Arizona +10
Money is leaning the other way and the line still won't move — the book is comfortable. When a number holds under pressure, I side with the book: Arizona.
Over 44.5
The under is taking the money and the total hasn't budged — a number that won't move is a number the book likes. I take the over.

Three AI models, three reasoning styles, nine independent calls. Meet the picks desk →